Author

Koichi Saeki

Tokyo University of ScienceORCID 0000-0003-1886-8302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Hiroshi HaenoiD· 2 shared Carlos Bueso-RamosiD· 1 shared Chiraag Deepak KapadiaiD· 1 shared Chong ZhaoiD· 1 shared Courtney Denton DinardoiD· 1 shared Curtis E. GumbsiD· 1 shared Daisuke NakadaiD· 1 shared Elizabeth Shpall· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Hiroshi HaenoORCID

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2 papers

Recent·Most cited

BioinformaticsBriefings in BioinformaticsPeer-reviewedMay 1, 2026

geneSCOPE: gene Spatial Co-Occurrence of Pairwise Expression

Shicheng Zhang, Koichi Saeki, Hiroshi Haeno

geneSCOPE identifies spatial gene modules and cell-cell interactions by integrating ecology-inspired statistics and network analysis in spatial transcriptomics data.

DOI 10.1093/bib/bbag302

humanspatial transcriptomics

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Cancer BiologyNature GeneticsPeer-reviewedJul 1, 2025

Clonal evolution of hematopoietic stem cells after cancer chemotherapy

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno…·Koichi Takahashi

This study examines how chemotherapy affects clonal diversity and mutation patterns in hematopoietic stem cells, finding that melphalan increases mutational burden and promotes clonal aging, potentially leading to therapy-related myeloid neoplasms.

24 citationstop 1%

humanwhole-genome sequencing

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