Author

Hidetaka Uryu

The University of Texas MD Anderson Cancer CenterORCID 0000-0001-7167-895XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Albert JeltschiD· 1 shared Carlos Bueso-RamosiD· 1 shared Chiraag Deepak KapadiaiD· 1 shared Chong ZhaoiD· 1 shared Courtney Denton DinardoiD· 1 shared Curtis E. GumbsiD· 1 shared Daisuke NakadaiD· 1 shared Dongliang CheniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Albert JeltschORCID

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2 papers

Recent·Most cited

Cancer BiologyNature GeneticsPeer-reviewedJul 1, 2025

Clonal evolution of hematopoietic stem cells after cancer chemotherapy

Hidetaka Uryu, Koichi Saeki, Hiroshi Haeno…·Koichi Takahashi

This study examines how chemotherapy affects clonal diversity and mutation patterns in hematopoietic stem cells, finding that melphalan increases mutational burden and promotes clonal aging, potentially leading to therapy-related myeloid neoplasms.

24 citationstop 1%

humanwhole-genome sequencing

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GeneticsNature CommunicationsPeer-reviewedJul 3, 2020

Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms

Linfeng Gao, Max Emperle, Yiran Guo…·Jikui Song

This study characterizes the structure-function differences between DNMT3A and DNMT3B, revealing distinct mechanisms of de novo DNA methylation and their implications in epigenomic alterations.

199 citationstop 1%

humanDNA methylation

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