PhysiologybioRxivPreprint
Regulation of Pacemaker Current in the Sinoatrial Node by Zonula Occludens-1
Rui Zhang, Sarah Teboull, Dexin Chen…·Joshua I. Goldhaber
This study investigates the role of ZO-1 in sinoatrial node automaticity and finds that its loss reduces pacemaker current and impairs atrial conduction, leading to bradyarrhythmia.
DOI 10.64898/2026.05.19.726291