Holly Sue Hake

This paper uses Dynamic Causal Modeling on fMRI data to compare three basal ganglia connectivity models across cognitive tasks and resting state, finding the Mixed model performs best.

The paper investigates how alpha2-adrenergic receptors modulate noradrenaline-dependent synaptic transmission in the dorsal raphe nucleus, showing that 2-AR inhibit noradrenaline release and reduce serotonin neuron activity.

The paper develops an autoencoder model to explain the complex relationship between hippocampal size and memory function in Alzheimer's Disease, Autism Spectrum Disorder, and PTSD by simulating experience-dependent encoding.

The paper identifies a nucleus accumbens local circuit where excitatory plasticity and substance P release are essential for cue-dependent aversive learning and recall.

The paper demonstrates that GluD1R functions as a constitutively active ion channel in dorsal raphe neurons, mediating 1-AR-induced inward current and pacemaker firing.