Author

Peter A. Friedman

University of PittsburghORCID 0000-0003-1905-1468Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

John R. HepleriD· 2 shared W. Bruce SneddoniD· 2 shared Clara E. Magyar· 1 shared David R. Emlet· 1 shared G. Emme Van DoorniD· 1 shared Katherine E. SquiresiD· 1 shared Suneela Ramineni· 1 shared Tatyana Mamonova· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

John R. HeplerORCID

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2 papers

Recent·Most cited

Cell BiologyBiochemical JournalPeer-reviewedJan 10, 2025

Structural factors of RGS14 regulating hormone-dependent phosphate transport mediated by NPT2A

W. Bruce Sneddon, Suneela Ramineni, G. Emme Van Doorn…·Peter A. Friedman

This study identifies structural elements of RGS14 that regulate hormone-sensitive phosphate transport by NPT2A, showing that phosphorylation in the linker and an intact PDZ ligand are essential.

3 citations

proteomicsexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintFeb 5, 2019

Genetic variants disrupt human RGS14 binding to NHERF1 and regulation of NPT2A-mediated phosphate transport

Peter A. Friedman, Tatyana Mamonova, Clara E. Magyar…·John R. Hepler

This study identifies how genetic variants in RGS14 affect its interaction with NHERF1 and regulation of phosphate transport, showing some variants disrupt binding while others maintain function.

DOI 10.1101/540781

humanproteomics

𝕏 PostBluesky