Cancer BiologyEBioMedicinePeer-reviewed
Deletions Rate-Limit Breast and Ovarian Cancer Initiation
Kathleen E. Houlahan, Mahad Bihie, Yves Greatti…·Kuan-lin Huang
The paper identifies genomic deletions as the rate-limiting mutational processes in breast and ovarian cancer initiation, requiring 1-3 deletions for tumor development.
DOI 10.1016/j.ebiom.2026.106181