Author

Ryo Fujisawa

Harvard UniversityORCID 0000-0003-1985-1668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Karim P. M. LabibiD· 2 shared Cristian Polo RiveraiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersCell Biology

Karim P. M. LabibORCID

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2 papers

Recent·Most cited

Cell BiologySciencePeer-reviewedJul 2, 2026

TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Pol epsilon

Ryo Fujisawa, Karim P. M. Labib

The paper identifies TTF2 as a regulator that couples TRAIP to Pol epsilon, enabling TRAIP to ubiquitylate the CMG helicase and drive replisome disassembly and MiDAS during mitosis.

11 citationstop 1%

humanproteomics

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Molecular BiologyeLifePeer-reviewedAug 3, 2022

Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase

Ryo Fujisawa, Cristian Polo Rivera, Karim P. M. Labib

The paper shows that UBX proteins lower the ubiquitin threshold for p97-UFD1-NPL4 to unfold substrates, similar to yeast.

37 citations

yeasthuman

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