Author

Simon Guiraud

InsermORCID 0000-0003-1987-7454Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Anne De CianiD· 1 shared Benjamin Edwards· 1 shared Fatima Amor· 1 shared Fetta MazediD· 1 shared Francesco Saverio TedescoiD· 1 shared Giuseppe RonzittiiD· 1 shared Isabelle RichardiD· 1 shared Kay Elizabeth DaviesiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Anne De CianORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 16, 2026

Regeneration-associated utrophin expression in skeletal muscle: implications for utrophin-targeted therapies

Simon Guiraud, Benjamin Edwards, Sarah E. Squire, Kay Elizabeth Davies

This study shows that utrophin expression in skeletal muscle is closely tied to regeneration phases and cannot be used alone to assess therapeutic effects, suggesting the need for combined markers.

DOI 10.64898/2026.09.10.750746

mouseprotein structure

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Molecular BiologybioRxivPreprintApr 18, 2023

CRISPR-Cas9 mediated endogenous utrophin upregulation improves Duchenne Muscular Dystrophy

Simon Guiraud, Sumitava Dastidar, Fetta Mazed…·Mario Amendola

This study uses CRISPR-Cas9 to disrupt miR binding sites and upregulate utrophin in DMD models, showing functional improvements and therapeutic potential.

DOI 10.1101/2023.04.18.536394

humanmouse

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