Michael Joseph Strong

This study investigates how SARS-CoV-2 N-protein forms biomolecular condensates and interacts with ALS-associated RNA-binding proteins in vitro and human cell models.

This study identifies ARPP21 as a TDP-43-independent aggregation pathway in ALS, showing its role in forming non-ubiquitinated aggregates and promoting intercellular propagation.

The paper investigates how 3' UTR variants of ALS-linked RNAs affect cell morphology and function in neuronal cells.

The paper shows TDP-43 and RGNEF regulate axon guidance genes through their opposing effects on long-intron processing in neuronal-like cells.

This study shows that expressing a RGNEF N-terminal fragment mitigates TDP-43 toxicity in ALS models by reducing aggregation and neurodegeneration.

This study examines the relationship between white matter hyperintensities, cortical thickness, and empathy in neurodegenerative and cerebrovascular diseases, finding associations with specific brain regions and demographic factors.