BiochemistryReceptorsPeer-reviewed
LPA3: Pharmacodynamic differences between lysophosphatidic acid and oleoyl-methoxy glycerophosphothionate. Biased agonism, two sites.
Karina Helivier Solís, María Teresa Romero‐Ávila, Ruth Rincón-Heredia…·Jesús Adolfo García-Sáinz
The paper compares the pharmacodynamic effects of LPA and OMPT on LPA3 receptors, revealing differences in signaling, internalization, and refractory states, suggesting the existence of two binding sites.