Tuning Encodable Tetrazine Chemistry for Site-Specific Protein Bioorthogonal Ligations
Subhashis Jana, Alex J. Eddins, Yogesh M. Gangarde, P. Andrew Karplus, Ryan A. Mehl
This study develops a highly reactive and stable tetrazine amino acid for site-specific protein labeling, demonstrating improved encoding and ligation efficiency.
Angewandte Chemie International Edition · Jul 3, 2025Peer-reviewedBiochemistry