Molecular BiologybioRxivPreprint
High-Throughput Measurement of Metastable DNA Secondary Structures Using Multiplexed Low-Yield Bisulfite Sequencing (MLB-seq)
Jiaming Li, Jin H. Bae, Boyan Yordanov…·David Yu Zhang
This paper introduces MLB-seq, a method to profile DNA secondary structures using bisulfite sequencing, and finds that 84% of studied human genome subsequences adopt multiple structures.
DOI 10.1101/2021.05.21.445174