Michael Wang

Seqwin identifies microbial signature sequences by analyzing large genome collections, outperforming existing methods in efficiency and quality.

The paper identifies DFFB as a mechanism by which cancer persister cells suppress interferon to escape growth arrest and regrow after oncogene-targeted therapy.

The paper identifies antigenic cancer persister cells that survive direct T cell attack by leveraging apoptosis to avoid inflammatory death and acquiring mutations for immune resistance.

Olivar automates variant-aware primer design for tiled amplicon sequencing of pathogens, improving mapping rates and coverage compared to existing methods.

This paper introduces MLB-seq, a method to profile DNA secondary structures using bisulfite sequencing, and finds that 84% of studied human genome subsequences adopt multiple structures.