Author

Alec Uebersohn

Gladstone InstitutesORCID 0000-0003-2052-8358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Benoit G. BruneauiD· 2 shared Elphège Pierre NoraiD· 2 shared Leonid A. MirnyiD· 2 shared Abigail NagleiD· 1 shared Agnès Le Saux· 1 shared Anne-Laure ValtoniD· 1 shared Antoine CouloniD· 1 shared Anton A. GoloborodkoiD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Benoit G. BruneauORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedNov 5, 2020

Molecular basis of CTCF binding polarity in genome folding

Elphège Pierre Nora, Laura Caccianini, Geoffrey Fudenberg…·Benoit G. Bruneau

The paper investigates how CTCF binding polarity influences chromatin loop formation by showing that CTCF positions cohesin but does not control its binding dynamics.

214 citationstop 1%

humanChIP-seq

𝕏 PostBluesky

GenomicsCellPeer-reviewedMay 1, 2017

Targeted degradation of CTCF decouples local insulation of chromosome domains from higher-order genomic compartmentalization

Elphège Pierre Nora, Anton A. Goloborodko, Anne-Laure Valton…·Benoit G. Bruneau

This study shows CTCF is essential for TAD organization but not for genome compartmentalization, revealing distinct mechanisms for chromatin folding and insulation.

1,708 citationstop 1%

mouseChIP-seq

𝕏 PostBluesky