Anne-Laure Valton

The paper identifies dimeric G-quadruplex motifs as key determinants of replication origins by inducing nucleosome-free regions and H2A.Z enrichment in vertebrates.

The paper identifies three types of chromatin boundaries that regulate cohesin traffic, which guides enhancer-promoter interactions and affects gene regulation.

The paper shows that during telophase, condensin-mediated loops are replaced by cohesin-mediated loops and TADs, revealing telophase as a critical transition in chromosome folding.

This study investigates cell-to-cell and cell-intrinsic variability in genome organization using Hi-C and genome imaging in human fibroblasts, revealing extensive heterogeneity in chromatin conformations.

This study shows CTCF is essential for TAD organization but not for genome compartmentalization, revealing distinct mechanisms for chromatin folding and insulation.