Author
Centre National de la Recherche ScientifiqueORCID 0000-0002-8610-8543Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Manuel Osorio‐Valeriano, Alexander C. Stone, Masahiro Nagano…·Seychelle M. Vos
CTCF dimerization on stacked nucleosomes is resolved by cryo-EM through a ZnF6-7-8 interface. Disrupting it in mouse stem cells weakens CTCF-cohesin loops more than insulation and impairs germline differentiation.
Emily Winther Sørensen, Sushil Pangeni, Raquel Merino‐Urteaga…·Taekjip Ha
DNAsight automates AFM image analysis of chromatin organization, revealing protein-specific structural signatures and nucleosome spacing distributions.
Sergei Rudnizky, Peter J Murray, Emily Winther Sørensen…·Taekjip Ha
The paper shows CTCF controls chromatin boundary permeability through a dynamic conformational ensemble, not static occupancy, influencing cohesin capture probabilities.
Sheldon Decombe, François Loll, Laura Caccianini…·Judith Lopes
The paper shows that reducing H3K9me3 at centromeric repeats using TALE-JMJD2B increases chromatin accessibility and causes chromosomal instability.
Elphège Pierre Nora, Laura Caccianini, Geoffrey Fudenberg…·Benoit G. Bruneau
The paper investigates how CTCF binding polarity influences chromatin loop formation by showing that CTCF positions cohesin but does not control its binding dynamics.