Author

Abigail Nagle

Gladstone InstitutesORCID 0000-0002-6200-8628Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Benoit G. BruneauiD· 2 shared Agnès Le Saux· 1 shared Alec UebersohniD· 1 shared Antoine CouloniD· 1 shared Bassam HajjiD· 1 shared Daniel Brambila-Diaz· 1 shared Dasom Yoo· 1 shared Elphège Pierre NoraiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMolecular Biology

Benoit G. BruneauORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintMar 18, 2025

Calcium-Activated Sarcomere Contractility Drives Cardiomyocyte Maturation and the Response to External Mechanical Cues but is Dispensable for Sarcomere Formation

Laura A. Sherer, Abigail Nagle, Mary Papadaki…·Jonathan A. Kirk

This study shows calcium-activated contractility is not needed for sarcomere formation but is essential for cardiomyocyte maturation and response to mechanical cues, with nanopatterns aiding maturation in non-contractile cells.

1 citation

humanproteomics

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Molecular BiologyNature CommunicationsPeer-reviewedNov 5, 2020

Molecular basis of CTCF binding polarity in genome folding

Elphège Pierre Nora, Laura Caccianini, Geoffrey Fudenberg…·Benoit G. Bruneau

The paper investigates how CTCF binding polarity influences chromatin loop formation by showing that CTCF positions cohesin but does not control its binding dynamics.

214 citationstop 1%

humanChIP-seq

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Developmental BiologyDevelopmentPeer-reviewedNov 29, 2019

Minimal in vivo requirements for developmentally regulated cardiac long intergenic non-coding RNAs

Matthew George, Qiming Duan, Abigail Nagle…·Benoit G. Bruneau

The paper investigates the role of developmentally regulated cardiac lincRNAs in heart development and function, finding that their deletion does not cause severe cardiac phenotypes.

20 citations

mousebulk RNA-seq

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