GeneticsDevelopmentPeer-reviewed
Disrupting Pitx1 Regulatory Topology Results In Overtly Normal Limb Development
Richard Sarro, Acadia A. Kocher, Deena Emera…·James P. Noonan
The paper disrupts the major promoter-enhancer interaction for Pitx1 in mice and finds minimal phenotypic effects despite complete disruption of the topological interaction.
19 citations