Author

Deena Emera

Yale UniversityORCID 0000-0003-1034-3464Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

James P. NoonaniD· 3 shared Severin UebbingiD· 3 shared Acadia A. KocheriD· 2 shared Emily V. DutrowiD· 2 shared Timothy NottoliiD· 2 shared Angeliki LouviiD· 1 shared Daniel B. BurkhardtiD· 1 shared Evan T. GelleriD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersGenomics

James P. NoonanORCID

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3 papers

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedJan 13, 2022

Modeling uniquely human gene regulatory function in humanized mice

Emily V. Dutrow, Deena Emera, Kristina Yim…·James P. Noonan

The paper examines the role of the human-specific enhancer HACNS1 in human evolution by analyzing its effects on gene expression in humanized mice.

42 citations

mousebulk RNA-seq

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GenomicsbioRxivPreprintDec 2, 2019

Massively parallel disruption of enhancers active during human corticogenesis

Evan T. Geller, Jake Gockley, Deena Emera…·James P. Noonan

The paper disrupts enhancers and genes in human neural stem cells to study their effects on proliferation and identifies regulatory elements linked to neurodevelopmental disorders.

6 citations

humanCRISPR screen

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GeneticsDevelopmentPeer-reviewedMar 16, 2018

Disrupting Pitx1 Regulatory Topology Results In Overtly Normal Limb Development

Richard Sarro, Acadia A. Kocher, Deena Emera…·James P. Noonan

The paper disrupts the major promoter-enhancer interaction for Pitx1 in mice and finds minimal phenotypic effects despite complete disruption of the topological interaction.

19 citations

mouseDNA methylation

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