Author

Elan D. Louis

The University of Texas Southwestern Medical CenterORCID 0000-0003-2062-362XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Phyllis L. FaustiD· 2 shared Charles L. WhiteiD· 1 shared Hirofumi FujitaiD· 1 shared Jaime Vaquer‐AliceaiD· 1 shared James WidneriD· 1 shared Jemin ParkiD· 1 shared Lorraine N. ClarkiD· 1 shared Marc I. DiamondiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Phyllis L. FaustORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 26, 2025

Axonal pathology differentially affects human Purkinje cell subtypes in the essential tremor cerebellum

James Widner, Phyllis L. Faust, Elan D. Louis, Hirofumi Fujita

The paper identifies distinct Purkinje cell subtypes in the human cerebellum and shows differential vulnerability in essential tremor, with motor-related subtypes showing axonal pathology.

DOI 10.1101/2025.01.26.633063

humanspatial transcriptomics

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PathologyActa NeuropathologicaPeer-reviewedJan 8, 2025

Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy

Nil Saez-Calveras, Jaime Vaquer‐Alicea, Charles L. White…·Marc I. Diamond

This study identifies that tau assemblies in a subset of essential tremor cases with tau pathology are conformationally similar to Alzheimer's disease and primary age-related tauopathy.

8 citations

humanproteomics

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GeneticsPLoS ONEPeer-reviewedAug 12, 2019

Whole Genome Sequencing and Rare Variant Analysis in Essential Tremor Families

Zagaa Odgerel, Shilpa Sonti, Nora C. Hernandez…·Lorraine N. Clark

The paper uses whole genome sequencing to identify candidate genes for essential tremor in families, finding variants in CACNA1G and other genes associated with neuronal function and hereditary neuropathies.

36 citations

humanwhole-genome sequencing

𝕏 PostBluesky