Shilpa Sonti

The paper develops patient-derived airway organoids from BAL fluid to model BPD injury and therapy responses in vitro.

This study identifies rs3752495 as the causal variant at the insomnia WDR90 GWAS locus that influences PIG-Q expression through a regulatory mechanism.

The paper identifies GPI-anchor biosynthesis as a conserved regulator of sleep through variant-to-gene mapping and cross-species genetic screening in humans and model organisms.

The paper identifies conserved genes at insomnia GWAS loci using zebrafish CRISPR screens and chromatin interaction data, finding that MEIS1 and SKIV2L mutations produce insomnia-like behaviors.

The paper uses whole genome sequencing to identify candidate genes for essential tremor in families, finding variants in CACNA1G and other genes associated with neuronal function and hereditary neuropathies.