Nicholas A. Willis

The paper shows that defective BRCA1-mediated DNA end resection leads to Group 1 tandem duplication formation and FANCM synthetic lethality in mouse models.

This study identifies NDRG1 as a DNA repair protein that links pancreatic cancer stroma to chemoresistance by enhancing DNA damage repair through R-loop resolution.

This study investigates Flp-nickase-induced homologous recombination, revealing two-ended repair mechanisms and their dependence on BRCA1 and BRCA2/RAD51.

This study identifies FANCM's role in regulating repair pathway choice at stalled replication forks and highlights its ATPase function as a potential therapeutic target for BRCA1 mutant cancers.