King Ifashe

The paper reverse-engineers a TCR to reduce cross-reactivity while maintaining potency by reverting specific residues.

ABB4-STEROIDS generates antibody conformational ensembles with state-of-the-art accuracy, outperforming existing methods in experimental benchmarks.

This study introduces a molecular dynamics model and databases to analyze CDR loop flexibility in antibodies and TCRs, enabling detailed study of their dynamics and machine learning training.