GenomicsNature GeneticsPeer-reviewed
Dissecting tumor transcriptional heterogeneity from single-cell RNA-seq data by generalized binary covariance decomposition
Yusha Liu, Peter S. Carbonetto, Jason Willwerscheid…·Matthew Stephens
This paper introduces GBCD to decompose tumor transcriptional heterogeneity in scRNA-seq data, identifying a new prognostic gene expression program in pancreatic cancer.