Interferon Restores Antigen Presentation and Sensitizes Medulloblastoma to T Cell Killing
Tanja Eisemann, Meher Beigi Masihi, Theophilos Tzaridis, Veronika I. Pister, Isaac Youm, Kendall R. Chambers, Aditi Dutta, Alexander T. Wenzel, Koei Chin, Scott L. Pomeroy, Jill P. Mesirov, Ernest Fraenkel, Anindya Bagchi, Lukas Chávez, Robert J. Wechsler‐Reya
This study shows that interferon gamma restores antigen presentation in medulloblastoma and enhances T cell-mediated tumor killing in a mouse model.
bioRxiv · Sep 30, 2025 · PreprintCancer Biology