Amel Ben Saad

This study models the MTARC1 A165T variant in human liver organoids, showing reduced steatosis, inflammation, and fibrosis compared to reference sequence organoids.

Singletrome enhances scRNA-seq analysis by integrating lncRNA annotations, improving mapping specificity and enabling lncRNA-based cell type clustering and disease prediction.

The paper evaluates three NAFLD liver organoid models using single-cell transcriptomics, finding TGF-β1 induces fibrosis while OA reduces fibrotic signatures.