Hilde Loge Nilsen

The paper establishes a high-throughput screening dataset of small-molecule inhibitors across nine human DNA glycosylases, identifying previously unreported inhibitors and making data publicly available.

This study shows that NTHL1 loss increases mtDNA copy number and mitochondrial function, enhancing cellular resilience to oxidative stress through stress response pathways.

This study identifies dUTPase as a mitotic regulator essential for early embryonic development, showing its role in centrosome integrity and spindle dynamics beyond its known nucleotide sanitization function.

This study shows that nicotinamide riboside (NR) alleviates Parkinson's disease symptoms in animal models but reduces dopamine levels when combined with proteasome inhibition.