Heng‐Chang Chen

The paper identifies CpG methylation and methionine metabolism as factors contributing to phenotypic bifurcation in HIV transcription, suggesting a pure epigenetic mechanism.

The paper identifies distinct intrinsic sequence patterns between HIV-1 DNA and RNA across subtypes using a k-mer-based approach and presents a new tool for genomic analysis.

This study investigates how HIV sense and antisense transcripts influence stochastic HIV transcription and reactivation through chromosomal and integration site-related fluctuations.

The paper identifies SARS-CoV-2 genetic markers associated with host domestication using a k-mer-based pipeline, revealing mutations and host-specific genomic patterns.

This study uses graph theory to analyze topological properties of HIV-1 reservoir networks, revealing differences between elite controllers and ART-treated patients.

The paper identifies spatially clustered genes with multiple enhancers as frequent targets of HIV-1 integration in T cells.