Author

Matheus Brandemarte Severino

Universidade de São PauloORCID 0000-0003-2124-4146Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Fernando Moreira SimabucoiD· 2 shared Isadora Carolina Betim PavaniD· 2 shared Mariana Camargo Silva ManciniiD· 2 shared Mariana Marcela GóisiD· 2 shared Alexandre Leite Rodrigues de OliveiraiD· 1 shared Ana Paula MorelliiD· 1 shared André Almeida SchenkaiD· 1 shared Ângela SaitoiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Fernando Moreira SimabucoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 28, 2026

GALR2 W248L mutation exacerbates neuroinflammation through pro-inflammatory macrophage polarization and microglial activation in experimental autoimmune encephalomyelitis

Raphael M. Neto, Danieli Cristina Gonçalves, Karina Degaki…·Ângela Saito

This study shows that the GALR2 W248L mutation worsens neuroinflammation by promoting pro-inflammatory macrophage polarization and microglial activation in EAE.

DOI 10.64898/2026.07.27.740554

mouseexperimental assay

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Molecular BiologybioRxivPreprintMay 8, 2026

S6K1 and S6K2 regulate homologous recombination DNA repair through control of BRCA1 protein stability

Mariana Marcela Góis, Lais Bonafe, L O Silva…·Fernando Moreira Simabuco

This study shows that S6K1 and S6K2 regulate BRCA1 stability and HR repair, with their double knockout increasing DNA damage sensitivity and genomic instability.

DOI 10.64898/2026.04.28.721439

humanexperimental assay

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Molecular BiologybioRxivPreprintDec 6, 2021

Characterization of the interaction between SARS-CoV-2 Membrane Protein and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target

Érika Pereira Zambalde, Isadora Carolina Betim Pavan, Mariana Camargo Silva Mancini…·Fernando Moreira Simabuco

The paper investigates the interaction between SARS-CoV-2 Membrane Protein and PCNA, showing cytoplasmic translocation of PCNA and its potential as a therapeutic target.

1 citation

humanproteomics

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