Author

Lais Bonafe

Universidade Estadual de Campinas (UNICAMP)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Fernando Moreira SimabucoiD· 1 shared Isadora Carolina Betim PavaniD· 1 shared L O Silva· 1 shared Mariana Camargo Silva ManciniiD· 1 shared Mariana Marcela GóisiD· 1 shared Matheus Brandemarte SeverinoiD· 1 shared Nathalia Quintero RuiziD· 1 shared Rosalie A. KampeniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Fernando Moreira SimabucoORCID

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1 paper

Recent·Most cited

S6K1 and S6K2 regulate homologous recombination DNA repair through control of BRCA1 protein stability

Mariana Marcela Góis, Lais Bonafe, L O Silva, Mariana Camargo Silva Mancini, Rosalie A. Kampen, Isadora Carolina Betim Pavan, Matheus Brandemarte Severino, Nathalia Quintero Ruiz, Sylvie M. Noordermeer, Fernando Moreira Simabuco

This study shows that S6K1 and S6K2 regulate BRCA1 stability and HR repair, with their double knockout increasing DNA damage sensitivity and genomic instability.

bioRxiv · May 8, 2026 · PreprintMolecular Biology