Lukas K. MacMillen

This study shows that voluntary social engagement after nerve injury reduces pain sensitivity, but only within a specific time window.

This paper develops an oral fentanyl self-administration model in mice to study escalation and relapse phenotypes, finding genetic background influences on these behaviors.

The paper identifies brain-wide neural circuits activated by isoflurane anesthesia and shows chemogenetic manipulation of these circuits reproduces key aspects of unconsciousness.

The paper maps whole-brain neural activity during emergence from isoflurane anesthesia in mice and finds selective subcortical activation rather than global cortical reactivation.