Molecular BiologybioRxivPreprint
Structures of human Malic Enzyme 3
Tsehai A.J. Grell, Mark M. Mason, Aaron A. Thompson…·Xiaodi Yu
This study determines the structures of human Malic Enzyme 3 (ME3) in various ligand binding states, revealing its tetrameric structure and dynamic Domain C, and provides insights into its non-allosteric nature and potential for drug development.
DOI 10.1101/2022.08.25.505315