Author

Kelsey A. Fryer

Stanford MedicineORCID 0000-0003-2140-9908Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:ChIP-seq· 4 Research Focus:gene regulatory network inference· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Aaron F. StraightiD· 4 shared Charles LimouseiD· 3 shared Owen K. SmithiD· 2 shared Aruni P. SenaratneiD· 1 shared David JukamiD· 1 shared Héloïse MulleriD· 1 shared Ines Anna DrinnenbergiD· 1 shared Jacob Price SchwartziD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersGenomics

Aaron F. StraightORCID

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5 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 1, 2025

Histone H3 lysine methyltransferase activities control compartmentalization of human centromeres.

Pragya Sidhwani, Jacob Price Schwartz, Kelsey A. Fryer, Aaron F. Straight

This study identifies the role of H3K9 methyltransferases in maintaining centromere compartmentalization by regulating CENP-A and heterochromatin distribution.

7 citations

humanDNA methylation

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GenomicsbioRxivPreprintJun 5, 2025

Identification of chromatin-associated RNAs at human centromeres

Kelsey A. Fryer, Charles Limouse, Aaron F. Straight

The paper identifies and maps RNAs associated with human centromeres using ChAR-seq in three cell lines, revealing three categories of centromere-bound RNAs.

2 citations

humanChIP-seq

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GenomicsNature CommunicationsPeer-reviewedSep 28, 2023

Global mapping of RNA-chromatin contacts reveals a proximity-dominated connectivity model for ncRNA-gene interactions

Charles Limouse, Owen K. Smith, David Jukam…·Aaron F. Straight

The paper maps ncRNA-chromatin interactions in human embryonic stem cells and shows that ncRNAs predominantly interact with nearby genes.

29 citations

humanChIP-seq

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GenomicsGenome ResearchPeer-reviewedJun 1, 2021

Identification and characterization of centromeric sequences in Xenopus laevis

Owen K. Smith, Charles Limouse, Kelsey A. Fryer…·Aaron F. Straight

This study identifies and characterizes centromeric sequences in Xenopus laevis using CENP-A ChIP-seq and k-mer analysis, revealing diverse repeat sequences and mapping centromere positions on each chromosome.

24 citations

ChIP-seqstatistical model

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GenomicsbioRxivPreprintJul 9, 2020

The molecular architecture of CenH3-deficient holocentromeres in Lepidoptera is dependent on transcriptional and chromatin dynamics

Aruni P. Senaratne, Héloïse Muller, Kelsey A. Fryer, Ines Anna Drinnenberg

This study identifies a novel mechanism of holocentromere formation in Lepidoptera linked to low chromatin dynamics and CenH3 deficiency.

2 citations

ChIP-seqstatistical model

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