Owen K. Smith

The paper presents high-quality genomes and chromatin structure analyses of frogs, revealing conserved ancestral chromosomes and stable genome evolution.

The paper maps ncRNA-chromatin interactions in human embryonic stem cells and shows that ncRNAs predominantly interact with nearby genes.

DiMeLo-seq maps protein-DNA interactions genome-wide with single-molecule resolution by methylating DNA near binding sites and using long-read sequencing.

This study identifies and characterizes centromeric sequences in Xenopus laevis using CENP-A ChIP-seq and k-mer analysis, revealing diverse repeat sequences and mapping centromere positions on each chromosome.

This paper introduces ChAR-seq, a method to map RNA-to-DNA contacts genome-wide, identifying chromatin-bound RNA targets such as nascent transcripts and trans-associated RNAs.