ImmunologybioRxivPreprint
Pluripotent stem cell-derived siTNK cells attack tumors via a synthetic CD8-CD28 TCR complex
Xiujuan Zheng, Fan Zhang, Yunqing Lin…·Minghan Zhang
The paper generates siTNK cells from hPSCs using a synthetic TCR complex, showing tumor-specific cytotoxicity and anti-tumor activity in xenograft models.