Author

Chia‐Ling Chen

Institute of Molecular Biology, Academia SinicaORCID 0000-0003-2161-4362Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:fungi (other)· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ting‐Fang WangiD· 2 shared Wan-Chen LiiD· 2 shared Yu-Chien Chuang· 2 shared Cai‐Mei ZhengiD· 1 shared Cathy S.J. FanniD· 1 shared Chang‐Hsun HsiehiD· 1 shared Cheng-Che Eric LaniD· 1 shared Chi-Chin Sun· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenetics

Ting‐Fang WangORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintOct 21, 2024

Deleterious Variants Contribute Minimal Excess Risk in Large-Scale Testing

Yen‐Tsung Huang, En‐Yu Lai, Jia-Ying Su…·Chang‐Hsun Hsieh

The paper analyzes 292 disease-relevant deleterious variants in 486,956 participants to assess their risk differences, finding most have minimal impact.

1 citation

humanwhole-exome sequencing

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GeneticsbioRxivPreprintMay 21, 2019

Two different pathways for initiation of Trichoderma reesei Rad51-only meiotic recombination

Wan-Chen Li, Yu-Chien Chuang, Chia‐Ling Chen…·Ting‐Fang Wang

This study investigates Rad51-only meiotic recombination in Trichoderma reesei, showing reduced interhomolog recombination and crossover homeostasis after spo11 removal, and suggests Topoisomerase II may redundantly initiate recombination.

6 citations

fungi (other)experimental assay

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GenomicsBiotechnology for BiofuelsPeer-reviewedJul 3, 2017

Trichoderma reesei Complete Genome Sequence, Repeat-Induced Point Mutation And Partitioning Of CAZyme Gene Clusters

Wan-Chen Li, Chien‐Hao Huang, Chia‐Ling Chen…·Ting‐Fang Wang

The paper presents a high-quality genome assembly of Trichoderma reesei QM6a, reveals new sequences and AT-rich blocks, and demonstrates repeat-induced point mutation mechanisms.

120 citationstop 3%

fungi (other)whole-genome sequencing

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