Author

Geert J.L.H. van Leenders

Erasmus MCORCID 0000-0003-2176-9102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

John W.M. MartensiD· 2 shared Ameneh BazrafshaniD· 1 shared Andrea SacchettiiD· 1 shared Andrew StubbsiD· 1 shared Anna WojtuszkiewicziD· 1 shared Anne S. Bolijn· 1 shared Annelies de KleiniD· 1 shared Bart J. JansseniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBioinformatics

John W.M. MartensORCID

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3 papers

Recent·Most cited

Cancer BiologyCancer LettersPeer-reviewedJan 30, 2025

Integrative analysis of patient-derived tumoroids and ex vivo organoid modeling of ARID1A loss in bladder cancer reveals therapeutic molecular targets

Mathijs P. Scholtes, Maryam Akbarzadeh, Αλέξανδρος Γαλάρας…·Tokameh Mahmoudi

The paper identifies CHEK1 and BIRC5 as therapeutic targets in ARID1A-deficient bladder cancer using patient-derived tumoroids and public datasets.

14 citations

humanbulk RNA-seq

BioinformaticsbioRxivPreprintMay 17, 2021

Detection of fusion transcripts and their genomic breakpoints from RNA sequencing data

Youri Hoogstrate, Malgorzata A. Komor, René Böttcher…·Guido W Jenster

Dr. Disco identifies fusion transcripts and genomic breakpoints using non poly(A)-enriched RNA-seq data, revealing transcribed rearrangements and their expression effects in cancer samples.

1 citation

humanbulk RNA-seq

BioinformaticsGenomics Proteomics & BioinformaticsPeer-reviewedApr 1, 2020

DPHL: A pan-human protein mass spectrometry library for robust biomarker discovery using Data-Independent Acquisition and Parallel Reaction Monitoring

Tiansheng Zhu, Yi Zhu, Yue Xuan…·Tiannan Guo

The paper introduces DPHL, a pan-human protein mass spectrometry library built using DIA and PRM, and demonstrates its utility in identifying differentially expressed proteins in prostate cancer and DLBCL.

94 citationstop 2%

humanproteomics