Cancer BiologyJCI InsightPeer-reviewed
NOTCH1 Acts as a Tumor Suppressor That Induces Early Differentiation in Head and Neck Cancer
Chenfei Huang, Shhyam Moorthy, Qiuli Li…·Mitchell J. Frederick
This study clarifies that NOTCH1 acts as a tumor suppressor in head and neck cancer, reducing cancer stem cells and improving prognosis, despite conflicting prior reports.
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