Author

Adel K. El‐Naggar

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-7175-9466Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Abdullah A. OsmaniD· 1 shared Amit Agrawal· 1 shared André CorveloiD· 1 shared Anil KorkutiD· 1 shared Anne‐Katrin EmdeiD· 1 shared Birgit Stache-Crain· 1 shared Bo JiangiD· 1 shared Chenfei HuangiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

Abdullah A. OsmanORCID

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3 papers

Recent·Most cited

NOTCH1 Acts as a Tumor Suppressor That Induces Early Differentiation in Head and Neck Cancer

Chenfei Huang, Shhyam Moorthy, Qiuli Li, Kazi Mokim Ahmed, Kalil Saab, Defeng Deng, Jiping Wang, Xiayu Rao, Jiexin Zhang, Yuanxin Xi, Jing Wang, Zhiyi Liu, Noriaki Tanaka, David A. Wheeler, Eve Shinbrot, , Mitchell J. Frederick

This study clarifies that NOTCH1 acts as a tumor suppressor in head and neck cancer, reducing cancer stem cells and improving prognosis, despite conflicting prior reports.

JCI Insight · Apr 16, 2026Peer-reviewedCancer Biology

Multi-omics analysis identifies intrinsic Trp53 driven metastatic breast cancer subtypes.

Joy M. McDaniel, Rhiannon L. Morrissey, Gilda P. Chau, Xiaoping Su, Zach von Ruff, Anil Korkut, Vidhi Chandra, Lei Huo, Adel K. El‐Naggar, Guillermina Lozano

The paper identifies three intrinsic metastatic breast cancer subtypes driven by Trp53 mutations through multi-omics analysis, revealing distinct transcriptomic and genomic features.

bioRxiv · Feb 18, 2026 · PreprintCancer Biology

Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers

David E. Symer, Keiko Akagi, Heather M. Geiger, Song Tao Yang, Gaiyun Li, Anne‐Katrin Emde, Weihong Xiao, Bo Jiang, André Corvelo, Nora C. Toussaint, Jingfeng Li, Amit Agrawal, Enver K. Ozer, Adel K. El‐Naggar, Zoe Du, , Maura L. Gillison

This study identifies HPV integration hotspots in oropharyngeal cancers and shows their role in disrupting host gene expression and genomic stability.

Genome Research · Jan 1, 2022Peer-reviewedGenomics