Author

Eve Shinbrot

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

David A. WheeleriD· 2 shared Abdullah A. OsmaniD· 1 shared Adel K. El‐NaggariD· 1 shared Andrew D. CherniackiD· 1 shared Andrew J Mungall· 1 shared Andy Chu· 1 shared Bob Fulton· 1 shared Bradley Murray· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

David A. WheelerORCID

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Author profile →

3 papers

Recent·Most cited

NOTCH1 Acts as a Tumor Suppressor That Induces Early Differentiation in Head and Neck Cancer

Chenfei Huang, Shhyam Moorthy, Qiuli Li, Kazi Mokim Ahmed, Kalil Saab, Defeng Deng, Jiping Wang, Xiayu Rao, Jiexin Zhang, Yuanxin Xi, Jing Wang, Zhiyi Liu, Noriaki Tanaka, David A. Wheeler, Eve Shinbrot, , Mitchell J. Frederick

This study clarifies that NOTCH1 acts as a tumor suppressor in head and neck cancer, reducing cancer stem cells and improving prognosis, despite conflicting prior reports.

JCI Insight · Apr 16, 2026Peer-reviewedCancer Biology

Comprehensive characterization of genomic, transcriptomic and epigenomic artifacts introduced in formalin-fixed, paraffin-embedded tissues.

Erik J. Zmuda, Kyle R Covington, Cyriac Kandoth, Charlotte K.Y. Ng, Daniel J Weisenberger, Reanne Bowlby, Andy Chu, Richard Corbett, Denise Brooks, Andrew D. Cherniack, Bradley Murray, Shiyun Ling, Wei Zhao, Eve Shinbrot, Raymond S Lim, , Katherine A Hoadley

This study characterizes genomic, transcriptomic, and epigenomic artifacts in FFPE tissues and provides best practices to mitigate their impact on molecular analysis.

Cancer Genetics · Jun 6, 2017Peer-reviewedBioinformatics

Mutation signatures reveal biological processes in human cancer

Kyle R. Covington, Eve Shinbrot, David A. Wheeler

This study uses non-smooth NMF to analyze somatic mutation profiles from 7129 tumors, identifying 21 mutational signatures, including three APOBEC-related processes and geographic differences in signatures.

bioRxiv · Jan 13, 2016 · PreprintGenomics