Author

Erica S. Pledger

Fred Hutch Cancer CenterORCID 0000-0003-2180-9741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:Ribo-seq· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Christine A. Codomo· 1 shared Hatice S Kaya-Okur· 1 shared Jamie H. D. CateiD· 1 shared Jorja G. HenikoffiD· 1 shared Kami AhmadiD· 1 shared Lucas FergusoniD· 1 shared Navya Ambavaram· 1 shared Steven HenikoffiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Christine A. Codomo

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintDec 16, 2025

Translational Downregulation of 5' TOP mRNAs During T Cell Exhaustion

Erica S. Pledger, Navya Ambavaram, Lucas Ferguson, Jamie H. D. Cate

The paper identifies translational repression of 5' TOP mRNAs in exhausted human CD8+ T cells despite elevated mTOR activity.

DOI 10.64898/2025.12.15.694525

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GenomicsNature CommunicationsPeer-reviewedApr 29, 2019

CUT&Tag for efficient epigenomic profiling of small samples and single cells

Hatice S Kaya-Okur, Steven J. Wu, Christine A. Codomo…·Steven Henikoff

The paper introduces CUT&Tag, a method for high-resolution epigenomic profiling of small samples and single cells with low background and efficient library preparation.

2,187 citationstop 1%

ChIP-seqexperimental assay

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