Author
Fred Hutch Cancer CenterORCID 0000-0001-7670-5101Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Steven Henikoff, Jorja G. Henikoff
The paper identifies superabundant microRNAs transcribed from human rDNA spacer promoters and shows their independent export and potential as cancer biomarkers.
Steven Henikoff, Ye Zheng, Ronald M. Paranal…·Kami Ahmad
The paper identifies RNA Polymerase II hypertranscription at histone genes in cancer FFPE samples, linking it to tumor progression and aneuploidy.
Jay F. Sarthy, Michael P. Meers, Derek H. Janssens…·Steven Henikoff
This study shows that H3.1 and H3.3 K27M oncohistones affect chromatin landscapes differently in DMG cells, with H3.1K27M leading to loss of H3K27 trimethylation.
Steven Henikoff, Jorja G. Henikoff, Hatice S Kaya-Okur, Kami Ahmad
The paper introduces a modified CUT&Tag method that produces chromatin accessibility maps comparable to ATAC-seq by adjusting tagmentation conditions for H3K4me2 or H3K4me3.
Hatice S Kaya-Okur, Steven J. Wu, Christine A. Codomo…·Steven Henikoff
The paper introduces CUT&Tag, a method for high-resolution epigenomic profiling of small samples and single cells with low background and efficient library preparation.
Peter J. Skene, Jorja G. Henikoff, Steven Henikoff
The paper introduces an improved CUT&RUN protocol that enables high-quality epigenomic profiling with low cell numbers and reduced experimental time.