Author

Dieter Mielke

Duke UniversityORCID 0000-0003-2182-0510Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Guido FerrariiD· 2 shared Aaron G. SchmidtiD· 1 shared Abdolrahim Abbasi· 1 shared Alicia SatoiD· 1 shared Alonso HerediaiD· 1 shared Andrew Asakawa· 1 shared Anthony L. DeVico· 1 shared Arash AslanabadiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Guido FerrariORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 21, 2026

Elicitation of stem-directed antibodies in rhesus macaques by a conventional hemagglutinin immunogen

Shuqin Gu, Joel Finney, Kan Luo…·Michael Anthony Moody

This study shows that a conventional H1 HA trimer vaccine elicits stem-directed antibodies in rhesus macaques that provide broad protection against H1N1 and H5N1 influenza.

DOI 10.64898/2026.07.16.738984

ratexperimental assay

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BioengineeringStructurePeer-reviewedMay 14, 2025

A Comprehensive Engineering Strategy Improves Potency and Manufacturability of a Near Pan-neutralizing Antibody Against HIV

Mohammad M. Sajadi, Abdolrahim Abbasi, Zahra Rikhtegaran Tehrani…·Anthony L. DeVico

This study engineers an HIV broadly neutralizing antibody to improve its potency, antiviral activity, and manufacturability while maintaining safety and efficacy.

11 citationstop 4%

humanproteomics

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