Mechanical and molecular parameters that influence the tendon differentiation potential of C3H10T1/2 cells in 2D- and 3D-culture systems
Ludovic Gaut, Marie-Ange Bonnin, Cédrine Blavet, Isabelle Cacciapuoti, Monika Orpel, Mathias Mericskay, Delphine Duprez
This study identifies mechanical and molecular factors influencing tendon differentiation of C3H10T1/2 cells in 2D and 3D cultures, showing that silicone substrates and 3D fibrin environments enhance tendon marker expression.
Biology Open · Jan 1, 2020Peer-reviewedDevelopmental Biology