Mathias Mericskay

Myocardial disarray drives metabolic inefficiency in human cardiomyocytes

This study shows that structured alignment of cardiomyocytes improves mitochondrial function and bioenergetic efficiency, highlighting the role of cellular organization in heart health.

Nicotinamide riboside: A promising therapy for MI-induced acute kidney injury by upregulating nicotinamide phosphoribosyltransferase-mediated NAD levels

This study shows that nicotinamide riboside (NR) improves kidney function and reduces damage in mice after myocardial infarction by increasing NAD levels via NAMPT.

A cocktail of B vitamins with nicotinamide riboside, folate and cobalamin preserves cardiac function and mitochondrial oxidative capacities in a mouse model of heart failure.

This study shows that a B vitamin cocktail improves cardiac function and mitochondrial health in a mouse heart failure model, with sex-specific effects.

Mechanical and molecular parameters that influence the tendon differentiation potential of C3H10T1/2 cells in 2D- and 3D-culture systems

This study identifies mechanical and molecular factors influencing tendon differentiation of C3H10T1/2 cells in 2D and 3D cultures, showing that silicone substrates and 3D fibrin environments enhance tendon marker expression.