Author

Christine Darko

Weill Cornell MedicineORCID 0000-0003-2199-8415Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew Rappa· 2 shared Anthony A. SauveiD· 1 shared Jeffery S. TessemiD· 1 shared Karina FariasiD· 1 shared Laura C. AlonsoiD· 1 shared Qingxia HuangiD· 1 shared Rohit B. SharmaiD· 1 shared Tara Doma Lama· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Andrew Rappa

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 11, 2026

MEF2A is a negative regulator of β-Cell maturation and function

Ying Wang, Christine Darko, Tara Doma Lama…·Rohit B. Sharma

This study identifies MEF2A as a negative regulator of beta cell maturation and function, showing that its overexpression impairs beta cell identity and insulin secretion under ER stress.

DOI 10.64898/2026.03.09.710500

mousebulk RNA-seq

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Pharmacology & ToxicologyMetabolismPeer-reviewedAug 30, 2024

NRH, a potent NAD+ booster, improves glucose homeostasis and lipid metabolism in diet-induced obese mice though an active adenosine kinase pathway.

Xinliu Zeng, Yongjie Wang, Karina Farias…·Yue Jin Yang

6 citations

mouseexperimental assay

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