Author

Jackson E. Powell

University of Illinois Urbana-ChampaignORCID 0000-0003-2207-4468Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Alisha Y. XiongiD· 1 shared Colin K.W. LimiD· 1 shared Jenny M. DrnevichiD· 1 shared M. Alejandra Zeballos C.iD· 1 shared Mayuri Singh· 1 shared Najah S. Ahsan· 1 shared Sijia ZhangiD· 1 shared Thomas GajiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Alisha Y. XiongORCID

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1 paper

Recent·Most cited

BioengineeringNature CommunicationsPeer-reviewedJan 8, 2025

A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD

Tristan X. McCallister, Colin K.W. Lim, Mayuri Singh…·Thomas Gaj

This study develops a high-fidelity CRISPR-Cas13 system that reduces C9ORF72 repeat RNA expression in a rodent model, decreasing RNA foci and reversing transcriptional deficits without affecting normal C9ORF72 levels.

19 citationstop 1%

mousegenetic perturbation / CRISPR

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