Author

Linda Pattini

Centro Cardiologico MonzinoORCID 0000-0003-2237-0961Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna Sorgente· 2 shared Emanuela FranchiniiD· 2 shared Giorgio CasariiD· 2 shared Irene SambriiD· 2 shared Katarína PAULÍKOVÁ· 2 shared Angelo QuattriniiD· 1 shared Ilaria Marafelli· 1 shared Laura CassinaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Anna Sorgente

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 7, 2026

Berberine improves motor deficits in the spastic paraplegia SPG7 mutant mice

Katarína PAULÍKOVÁ, Anna Sorgente, Emanuela Franchini…·Giorgio Casari

This study shows that berberine improves motor deficits in SPG7 mutant mice by modulating mitochondrial permeability transition pore dynamics.

DOI 10.64898/2026.06.25.734493

mouseexperimental assay

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Pharmacology & ToxicologyPharmacological ResearchPeer-reviewedMay 7, 2026

Pharmacological Restoration of Mitochondrial Permeability Transition Pore Flickering by High-Content Drug Repurposing

Emanuela Franchini, Matteo Bulloni, Anna Sorgente…·Giorgio Casari

This study identifies berberine as a compound that enhances mitochondrial permeability transition pore flickering, offering a potential therapeutic strategy for disorders like SPG7.

1 citation

humanproteomics

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