Dual Preconditioned Mesenchymal Stem Cells-Derived Culture Conditioned Media Augment Immunomodulation and Drive Metabolic Reprogramming in Acute Graft-versus-Host Disease
Mohini Mendiratta, Meenakshi Mendiratta, Sandeep Rai…·Ranjit Kumar Sahoo
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All India Institute of Medical SciencesORCID 0000-0003-2238-6015Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Mohini Mendiratta, Meenakshi Mendiratta, Sandeep Rai…·Ranjit Kumar Sahoo
Shabnam Ansari, Dipanka Tanu Sarmah, Rohit Verma…·Milan Surjit
This study identifies CK1ε as an antiviral target for HEV and shows that Etravirine, an HIV drug, inhibits CK1ε to exhibit antiviral activity against HEV.
Mohini Mendiratta, Praful Pandey, Shobhit Pandey…·Ranjit Kumar Sahoo
This study uses machine learning to predict acute Graft-versus-Host-Disease (aGvHD) based on immune cell and cytokine profiles at engraftment, finding high accuracy with cytokine and T-cell data.
Mohini Mendiratta, Meenakshi Mendiratta, Lakshay Malhotra…·Ranjit Kumar Sahoo
This study compares the immunomodulatory effects of hypoxia-preconditioned bone marrow and Wharton's jelly mesenchymal stem cells in acute graft-versus-host disease, finding WJ-MSCsHYP more effective due to enhanced mitochondrial transfer and metabolic reprogramming.
Mohini Mendiratta, Meenakshi Mendiratta, Shuvadeep Ganguly…·Ranjit Kumar Sahoo
This study shows that hypoxia and apoptosis conditioning of WJ-MSCs enhances their immune regulatory capacity in aGVHD by promoting Treg differentiation and M2 macrophage polarization.