Tim Davies

Mechanical coordination between anaphase A and B drives asymmetric chromosome segregation

The paper identifies a novel anaphase A mechanism in C. elegans embryos driven by KLP-7MCAK and opposed by KLP-18, showing its role in asymmetric chromosome segregation and mechanical coordination with anaphase B.

FHOD-1 is the only formin in Caenorhabditis elegans that promotes striated muscle growth and Z-line organization in a cell autonomous manner

This study identifies FHOD-1 as the sole formin required for striated muscle growth and Z-line organization in C. elegans through cell autonomous mechanisms.